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Block of an ether-a-go-go-Like K(+) Channel by Imipramine Rescues egl-2 Excitation Defects inCaenorhabditis elegans
K(+) channels are key regulators of cellular excitability. Mutations that activate K(+) channels can lower cellular excitability, whereas those that inhibit K(+) channels may increase excitability. We show that the Caenorhabditis elegansegl-2 gene encodes an eag K(+) channel and that a gain-of-funct...
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| Publicado en: | J Neurosci |
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| Autores principales: | , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Society for Neuroscience
1999
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6782970/ https://ncbi.nlm.nih.gov/pubmed/10559392 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.19-22-09831.1999 |
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