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A Murine Neural-Specific Homolog Corrects Cholinergic Defects inCaenorhabditis elegans unc-18 Mutants
Caenorhabditis elegans UNC-18 protein, homologous to yeast Sec1p, is important in neurotransmitter release, because theunc-18 mutation leads to severe paralysis and presynaptic acetylcholine (ACh) accumulation. To examine the functional conservation in mammals, we tried to isolate unc-18isoforms fro...
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| Publicado en: | J Neurosci |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Society for Neuroscience
1996
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6579271/ https://ncbi.nlm.nih.gov/pubmed/8824310 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.16-21-06695.1996 |
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