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A Murine Neural-Specific Homolog Corrects Cholinergic Defects inCaenorhabditis elegans unc-18 Mutants

Caenorhabditis elegans UNC-18 protein, homologous to yeast Sec1p, is important in neurotransmitter release, because theunc-18 mutation leads to severe paralysis and presynaptic acetylcholine (ACh) accumulation. To examine the functional conservation in mammals, we tried to isolate unc-18isoforms fro...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Gengyo-Ando, Keiko, Kitayama, Hitoshi, Mukaida, Masahiro, Ikawa, Yoji
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 1996
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6579271/
https://ncbi.nlm.nih.gov/pubmed/8824310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.16-21-06695.1996
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