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Protein phosphatase 2A cooperates with the autophagy-related kinase UNC-51 to regulate axon guidance in Caenorhabditis elegans

UNC-51 is a serine/threonine protein kinase conserved from yeast to humans. The yeast homolog Atg1 regulates autophagy (catabolic membrane trafficking) required for surviving starvation. In C. elegans, UNC-51 regulates the axon guidance of many neurons by a different mechanism than it and its homolo...

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Autori principali: Ogura, Ken-ichi, Okada, Takako, Mitani, Shohei, Gengyo-Ando, Keiko, Baillie, David L., Kohara, Yuji, Goshima, Yoshio
Natura: Artigo
Lingua:Inglês
Pubblicazione: Company of Biologists 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3188576/
https://ncbi.nlm.nih.gov/pubmed/20392746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.050708
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