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Knockdown of AMPA Receptor GluR2 Expression Causes Delayed Neurodegeneration and Increases Damage by Sublethal Ischemia in Hippocampal CA1 and CA3 Neurons

Considerable evidence suggests that Ca(2+)-permeable AMPA receptors are critical mediators of the delayed, selective neuronal death associated with transient global ischemia and sustained seizures. Global ischemia suppresses mRNA and protein expression of the glutamate receptor subunit GluR2 and inc...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Oguro, Keiji, Oguro, Noriko, Kojima, Takashi, Grooms, Sonja Y., Calderone, Agata, Zheng, Xin, Bennett, Michael V. L., Zukin, R. Suzanne
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6782923/
https://ncbi.nlm.nih.gov/pubmed/10531425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.19-21-09218.1999
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