Knockdown of AMPA Receptor GluR2 Expression Causes Delayed Neurodegeneration and Increases Damage by Sublethal Ischemia in Hippocampal CA1 and CA3 Neurons

Considerable evidence suggests that Ca(2+)-permeable AMPA receptors are critical mediators of the delayed, selective neuronal death associated with transient global ischemia and sustained seizures. Global ischemia suppresses mRNA and protein expression of the glutamate receptor subunit GluR2 and inc...

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Veröffentlicht in:J Neurosci
Hauptverfasser: Oguro, Keiji, Oguro, Noriko, Kojima, Takashi, Grooms, Sonja Y., Calderone, Agata, Zheng, Xin, Bennett, Michael V. L., Zukin, R. Suzanne
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 1999
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6782923/
https://ncbi.nlm.nih.gov/pubmed/10531425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.19-21-09218.1999
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