Hypothermia rescues hippocampal CA1 neurons and attenuates down-regulation of the AMPA receptor GluR2 subunit after forebrain ischemia

Brief forebrain ischemia in rodents induces selective and delayed neuronal death, particularly of hippocampal CA1 pyramidal neurons. Neuronal death is preceded by down-regulation specific to CA1 of GluR2, the α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor subunit that limits Ca...

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Bibliografiska uppgifter
Huvudupphovsmän: Colbourne, Frederick, Grooms, Sonja Y., Zukin, R. Suzanne, Buchan, Alastair M., Bennett, Michael V. L.
Materialtyp: Artigo
Språk:Inglês
Publicerad: The National Academy of Sciences 2003
Ämnen:
Biological Sciences
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC151439/
https://ncbi.nlm.nih.gov/pubmed/12606709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2628027100
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