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Sonic hedgehog Regulates Proliferation and Inhibits Differentiation of CNS Precursor Cells

Activation of the Sonic hedgehog (Shh) signal transduction pathway is essential for normal pattern formation and cellular differentiation in the developing CNS. However, it is also thought to be etiological in primitive neuroectodermal tumors. We adaptedGAL4/UAS methodology to ectopically express fu...

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Bibliografische gegevens
Gepubliceerd in:J Neurosci
Hoofdauteurs: Rowitch, David H., St.-Jacques, Benoit, Lee, Scott M. K., Flax, Jonathon D., Snyder, Evan Y., McMahon, Andrew P.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Society for Neuroscience 1999
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6782773/
https://ncbi.nlm.nih.gov/pubmed/10516314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.19-20-08954.1999
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