Sonic hedgehog Regulates Proliferation and Inhibits Differentiation of CNS Precursor Cells

Activation of the Sonic hedgehog (Shh) signal transduction pathway is essential for normal pattern formation and cellular differentiation in the developing CNS. However, it is also thought to be etiological in primitive neuroectodermal tumors. We adaptedGAL4/UAS methodology to ectopically express fu...

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Bibliografiske detaljer
Udgivet i:J Neurosci
Main Authors: Rowitch, David H., St.-Jacques, Benoit, Lee, Scott M. K., Flax, Jonathon D., Snyder, Evan Y., McMahon, Andrew P.
Format: Artigo
Sprog:Inglês
Udgivet: Society for Neuroscience 1999
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6782773/
https://ncbi.nlm.nih.gov/pubmed/10516314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.19-20-08954.1999
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