Sonic hedgehog Regulates Proliferation and Inhibits Differentiation of CNS Precursor Cells

Activation of the Sonic hedgehog (Shh) signal transduction pathway is essential for normal pattern formation and cellular differentiation in the developing CNS. However, it is also thought to be etiological in primitive neuroectodermal tumors. We adaptedGAL4/UAS methodology to ectopically express fu...

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Veröffentlicht in:J Neurosci
Hauptverfasser: Rowitch, David H., St.-Jacques, Benoit, Lee, Scott M. K., Flax, Jonathon D., Snyder, Evan Y., McMahon, Andrew P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 1999
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6782773/
https://ncbi.nlm.nih.gov/pubmed/10516314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.19-20-08954.1999
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