Sonic hedgehog Regulates Proliferation and Inhibits Differentiation of CNS Precursor Cells

Activation of the Sonic hedgehog (Shh) signal transduction pathway is essential for normal pattern formation and cellular differentiation in the developing CNS. However, it is also thought to be etiological in primitive neuroectodermal tumors. We adaptedGAL4/UAS methodology to ectopically express fu...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Rowitch, David H., St.-Jacques, Benoit, Lee, Scott M. K., Flax, Jonathon D., Snyder, Evan Y., McMahon, Andrew P.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 1999
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6782773/
https://ncbi.nlm.nih.gov/pubmed/10516314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.19-20-08954.1999
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