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Afferent–Target Cell Interactions in the Cerebellum: Negative Effect of Granule Cells on Purkinje Cell Development in Lurcher Mice

Lurcher (Lc) is a gain-of-function mutation in the δ2 glutamate receptor gene that results in a large, constitutive inward current in the cerebellar Purkinje cells of +/Lcmice. +/Lc Purkinje cells fail to differentiate fully and die during postnatal development. In normal mice, interactions with gra...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Doughty, Martin L., Lohof, Ann, Selimi, Fekrije, Delhaye-Bouchaud, Nicole, Mariani, Jean
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6782256/
https://ncbi.nlm.nih.gov/pubmed/10212305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.19-09-03448.1999
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