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Postnatal Expression of Hu-Bcl-2 Gene inLurcher Mutant Mice Fails to Rescue Purkinje Cells but Protects Inferior Olivary Neurons from Target-Related Cell Death
The Lurcher mutant has been extensively studied as a model for cell-autonomous and target-related cell death, yet there are still many unknowns concerning the mechanisms of neuronal degeneration in this mutant. As a key regulator of apoptosis, a bcl-2transgene has been overexpressed in the heterozyg...
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| Опубликовано в: : | J Neurosci |
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| Главные авторы: | , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Society for Neuroscience
1998
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6793412/ https://ncbi.nlm.nih.gov/pubmed/9412510 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.18-01-00319.1998 |
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