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Enhanced survival of wild type and Lurcher Purkinje cells in vitro following inhibition of conventional PKCs or stress-activated MAP kinase pathways

Recent studies using both dissociated and organotypic cell cultures have shown that heterozygous Lurcher (Lc/+) Purkinje cells (PCs) grown in vitro share many of the same survival and morphological characteristics as Lc/+ PCs in vivo. We have used this established tissue culture system as a valuable...

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Autors principals: Zanjani, Hadi S., Lohof, Ann M., McFarland, Rebecca, Vogel, Michael W., Mariani, Jean
Format: Artigo
Idioma:Inglês
Publicat: 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3582878/
https://ncbi.nlm.nih.gov/pubmed/23136008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12311-012-0427-x
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