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Prostaglandin E(2) Stimulates Amyloid Precursor Protein Gene Expression: Inhibition by Immunosuppressants
Amyloid plaques that accumulate in the brains of patients with Alzheimer’s disease (AD) are primarily composed of aggregates of amyloid peptides that are derived from the amyloid precursor protein (APP). Overexpression of APP in cell cultures increases the formation of amyloidogenic peptides and cau...
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| Publicado en: | J Neurosci |
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| Autores principales: | , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Society for Neuroscience
1999
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6782137/ https://ncbi.nlm.nih.gov/pubmed/9920657 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.19-03-00940.1999 |
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