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Early-life DNA methylation profiles are indicative of age-related transcriptome changes
BACKGROUND: Alterations to cellular and molecular programs with brain aging result in cognitive impairment and susceptibility to neurodegenerative disease. Changes in DNA methylation patterns, an epigenetic modification required for various CNS functions are observed with brain aging and can be prev...
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| Veröffentlicht in: | Epigenetics Chromatin |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BioMed Central
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6781367/ https://ncbi.nlm.nih.gov/pubmed/31594536 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13072-019-0306-5 |
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