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A role for PKD1 in insulin secretion downstream of P2Y(1) receptor activation in mouse and human islets
Along with insulin, β‐cells co‐secrete the neurotransmitter ATP which acts as a positive autocrine signal via P2Y(1) receptors to activate phospholipase C and increase the production of diacylglycerol (DAG). However, the downstream signaling that couples P2Y(1) activation to insulin secretion remain...
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| Publicado no: | Physiol Rep |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6779929/ https://ncbi.nlm.nih.gov/pubmed/31591827 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.14250 |
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