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Na/K Pump Mutations Associated with Primary Hyperaldosteronism Cause Loss of Function
Primary hyperaldosteronism (Conn’s syndrome), a common cause of secondary hypertension, is frequently produced by unilateral aldosterone-producing adenomas that carry mutations in ion-transporting genes, including ATP1A1, encoding the Na/K pump’s α1 subunit. Whether Na/K pump mutant-mediated inward...
Wedi'i Gadw mewn:
| Cyhoeddwyd yn: | Biochemistry |
|---|---|
| Prif Awduron: | , , |
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
2019
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6779590/ https://ncbi.nlm.nih.gov/pubmed/30811176 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.9b00051 |
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