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On the effect of hyperaldosteronism-inducing mutations in Na/K pumps

Primary aldosteronism, a condition in which too much aldosterone is produced and that leads to hypertension, is often initiated by an aldosterone-producing adenoma within the zona glomerulosa of the adrenal cortex. Somatic mutations of ATP1A1, encoding the Na/K pump α1 subunit, have been found in th...

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Vydáno v:J Gen Physiol
Hlavní autoři: Meyer, Dylan J., Gatto, Craig, Artigas, Pablo
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5677107/
https://ncbi.nlm.nih.gov/pubmed/29030398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201711827
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