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Altered Na(+) transport after an intracellular α-subunit deletion reveals strict external sequential release of Na(+) from the Na/K pump

The Na/K pump actively exports 3 Na(+) in exchange for 2 K(+) across the plasmalemma of animal cells. As in other P-type ATPases, pump function is more effective when the relative affinity for transported ions is altered as the ion binding sites alternate between opposite sides of the membrane. Dele...

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Main Authors: Yaragatupalli, Siddhartha, Olivera, J. Fernando, Gatto, Craig, Artigas, Pablo
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2741281/
https://ncbi.nlm.nih.gov/pubmed/19706387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0903752106
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