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Cebulantin, a Cryptic Lanthipeptide Antibiotic Uncovered via Bioactivity-Coupled HiTES
The majority of natural product biosynthetic gene clusters in bacteria are silent under standard laboratory growth conditions, making it challenging to uncover any antibiotics that they may encode. Herein we combine bioactivity assays with high-throughput elicitor screening (HiTES) to access cryptic...
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| Publicat a: | Angew Chem Int Ed Engl |
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| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6779416/ https://ncbi.nlm.nih.gov/pubmed/30843641 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201901342 |
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