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Bioactivity-HiTES Unveils Cryptic Antibiotics Encoded in Actinomycete Bacteria
Bacteria harbor an immense reservoir of potentially new and therapeutic small molecules in the form of ‘silent’ biosynthetic gene clusters (BGCs). These BGCs can be identified bioinformatically but are sparingly-expressed under normal laboratory growth conditions, or not at all, and therefore do not...
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| Udgivet i: | ACS Chem Biol |
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| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6813803/ https://ncbi.nlm.nih.gov/pubmed/30830740 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.9b00049 |
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