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Discovery of a Cryptic Antifungal Compound from Streptomyces albus J1074 Using High-Throughput Elicitor Screens

An important unresolved issue in microbial secondary metabolite production is the abundance of biosynthetic gene clusters that are not expressed under typical laboratory growth conditions. These so-called silent or cryptic gene clusters are sources of new natural products, but how they are silenced,...

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Pubblicato in:J Am Chem Soc
Autori principali: Xu, Fei, Nazari, Behnam, Moon, Kyuho, Bushin, Leah B., Seyedsayamdost, Mohammad R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5617735/
https://ncbi.nlm.nih.gov/pubmed/28590725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.7b02716
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