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Identification of butenolide regulatory system controlling secondary metabolism in Streptomyces albus J1074

A large majority of genome-encrypted chemical diversity in actinobacteria remains to be discovered, which is related to the low level of secondary metabolism genes expression. Here, we report the application of a reporter-guided screening strategy to activate cryptic polycyclic tetramate macrolactam...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Ahmed, Yousra, Rebets, Yuriy, Tokovenko, Bogdan, Brötz, Elke, Luzhetskyy, Andriy
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5575351/
https://ncbi.nlm.nih.gov/pubmed/28852167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-10316-y
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