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Cmr3 regulates the suppression on cyclic oligoadenylate synthesis by tag complementarity in a Type III-B CRISPR-Cas system

Type III CRISPR-Cas systems code for a multi-subunit ribonucleoprotein (RNP) complex that mediates DNA cleavage and synthesizes cyclic oligoadenylate (cOA) second messenger to confer anti-viral immunity. Both immune activities are to be activated upon binding to target RNA transcripts by their compl...

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Bibliografiske detaljer
Udgivet i:RNA Biol
Main Authors: Guo, Tong, Zheng, Fan, Zeng, Zhifeng, Yang, Yang, Li, Qi, She, Qunxin, Han, Wenyuan
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6779384/
https://ncbi.nlm.nih.gov/pubmed/31298604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15476286.2019.1642725
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