Cmr1 enables efficient RNA and DNA interference of a III-B CRISPR–Cas system by binding to target RNA and crRNA

CRISPR–Cas (clustered regularly interspaced short palindromic repeats-CRISPR-associated) systems provide adaptive immunity against invasive nucleic acids guided by CRISPR RNAs (crRNAs) in archaea and bacteria. Type III CRISPR–Cas effector complexes show RNA cleavage and RNA-activated DNA cleavage ac...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Li, Yingjun, Zhang, Yan, Lin, Jinzhong, Pan, Saifu, Han, Wenyuan, Peng, Nan, Liang, Yun Xiang, She, Qunxin
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Nucleic Acid Enzymes
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5737701/
https://ncbi.nlm.nih.gov/pubmed/28977458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx791
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