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DIVERSE SPATIAL EXPRESSION PATTERNS EMERGE FROM UNIFIED KINETICS OF TRANSCRIPTIONAL BURSTING

How transcriptional bursting relates to gene regulation is a central question that has persisted for more than a decade. Here, we measure nascent transcriptional activity in early Drosophila embryos and characterize the variability in absolute activity levels across expression boundaries. We demonst...

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Bibliografische gegevens
Gepubliceerd in:Cell
Hoofdauteurs: Zoller, Benjamin, Little, Shawn C., Gregor, Thomas
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2018
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6779125/
https://ncbi.nlm.nih.gov/pubmed/30340044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2018.09.056
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