Transcriptional Bursting and Co-bursting Regulation by Steroid Hormone Release Pattern and Transcription Factor Mobility

Genes are transcribed in a discontinuous pattern referred to as RNA bursting, but mechanisms regulating this process are unclear. Although many physiological signals, including glucocorticoid hormones, are pulsatile, the effects of transient stimulation on bursting are unknown. Here, we characterize...

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Pubblicato in:Mol Cell
Autori principali: Stavreva, Diana A., Garcia, David A., Fettweis, Gregory, Gudla, Prabhakar R., Zaki, George F., Soni, Vikas, McGowan, Andrew, Williams, Geneva, Huynh, Anh, Palangat, Murali, Schiltz, R. Louis, Johnson, Thomas A., Presman, Diego M., Ferguson, Matthew L., Pegoraro, Gianluca, Upadhyaya, Arpita, Hager, Gordon L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6754282/
https://ncbi.nlm.nih.gov/pubmed/31421980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2019.06.042
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