Transcriptional Bursting and Co-bursting Regulation by Steroid Hormone Release Pattern and Transcription Factor Mobility

Genes are transcribed in a discontinuous pattern referred to as RNA bursting, but mechanisms regulating this process are unclear. Although many physiological signals, including glucocorticoid hormones, are pulsatile, the effects of transient stimulation on bursting are unknown. Here, we characterize...

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Publicado no:Mol Cell
Main Authors: Stavreva, Diana A., Garcia, David A., Fettweis, Gregory, Gudla, Prabhakar R., Zaki, George F., Soni, Vikas, McGowan, Andrew, Williams, Geneva, Huynh, Anh, Palangat, Murali, Schiltz, R. Louis, Johnson, Thomas A., Presman, Diego M., Ferguson, Matthew L., Pegoraro, Gianluca, Upadhyaya, Arpita, Hager, Gordon L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6754282/
https://ncbi.nlm.nih.gov/pubmed/31421980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2019.06.042
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