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DIVERSE SPATIAL EXPRESSION PATTERNS EMERGE FROM UNIFIED KINETICS OF TRANSCRIPTIONAL BURSTING
How transcriptional bursting relates to gene regulation is a central question that has persisted for more than a decade. Here, we measure nascent transcriptional activity in early Drosophila embryos and characterize the variability in absolute activity levels across expression boundaries. We demonst...
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| Опубликовано в: : | Cell |
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| Главные авторы: | , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2018
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6779125/ https://ncbi.nlm.nih.gov/pubmed/30340044 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2018.09.056 |
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