G-tract RNA removes Polycomb Repressive Complex 2 from genes

Polycomb Repressive Complex 2 (PRC2) maintains repression of cell type-specific genes but also associates with genes ectopically in cancer. While it is currently unknown how PRC2 is removed from genes, such knowledge would be useful for the targeted reversal of deleterious PRC2 recruitment events. H...

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Detaylı Bibliyografya
Yayımlandı:Nat Struct Mol Biol
Asıl Yazarlar: Beltran, Manuel, Tavares, Manuel, Justin, Neil, Khandelwal, Garima, Ambrose, John, Foster, Benjamin M., Worlock, Kaylee B., Tvardovskiy, Andrey, Kunzelmann, Simone, Herrero, Javier, Bartke, Till, Gamblin, Steven J., Wilson, Jon R., Jenner, Richard G.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2019
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6778522/
https://ncbi.nlm.nih.gov/pubmed/31548724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41594-019-0293-z
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