Short RNAs are transcribed from repressed Polycomb target genes and interact with Polycomb Repressive Complex-2

Polycomb proteins maintain cell identity by repressing the expression of developmental regulators specific for other cell types. Polycomb repressive complex-2 (PRC2) catalyses trimethylation of histone H3 lysine-27 (H3K27me3). Although repressed, PRC2 targets are generally associated with the transc...

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Detalhes bibliográficos
Main Authors: Kanhere, Aditi, Viiri, Keijo, Araújo, Carla C., Rasaiyaah, Jane, Bouwman, Russell D., Whyte, Warren A., Pereira, C. Filipe, Brookes, Emily, Walker, Kimberly, Bell, George W., Pombo, Ana, Fisher, Amanda G., Young, Richard A., Jenner, Richard G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2886029/
https://ncbi.nlm.nih.gov/pubmed/20542000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2010.03.019
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