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Short RNAs are transcribed from repressed Polycomb target genes and interact with Polycomb Repressive Complex-2
Polycomb proteins maintain cell identity by repressing the expression of developmental regulators specific for other cell types. Polycomb repressive complex-2 (PRC2) catalyses trimethylation of histone H3 lysine-27 (H3K27me3). Although repressed, PRC2 targets are generally associated with the transc...
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| Главные авторы: | , , , , , , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2886029/ https://ncbi.nlm.nih.gov/pubmed/20542000 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2010.03.019 |
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