Short RNAs are transcribed from repressed Polycomb target genes and interact with Polycomb Repressive Complex-2

Polycomb proteins maintain cell identity by repressing the expression of developmental regulators specific for other cell types. Polycomb repressive complex-2 (PRC2) catalyses trimethylation of histone H3 lysine-27 (H3K27me3). Although repressed, PRC2 targets are generally associated with the transc...

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Autors principals: Kanhere, Aditi, Viiri, Keijo, Araújo, Carla C., Rasaiyaah, Jane, Bouwman, Russell D., Whyte, Warren A., Pereira, C. Filipe, Brookes, Emily, Walker, Kimberly, Bell, George W., Pombo, Ana, Fisher, Amanda G., Young, Richard A., Jenner, Richard G.
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2886029/
https://ncbi.nlm.nih.gov/pubmed/20542000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2010.03.019
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