Nalaganje...
Ligand-induced IFNGR1 down-regulation calibrates myeloid cell IFNγ responsiveness
The type II IFN (IFNγ) enhances antimicrobial activity yet also drives expression of genes that amplify inflammatory responses. Hence, excessive IFNγ stimulation can be pathogenic. Here, we describe a previously unappreciated mechanism whereby IFNγ itself dampens myeloid cell activation. Staining of...
Shranjeno v:
| izdano v: | Life Sci Alliance |
|---|---|
| Main Authors: | , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Life Science Alliance LLC
2019
|
| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6778285/ https://ncbi.nlm.nih.gov/pubmed/31585982 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.26508/lsa.201900447 |
| Oznake: |
Označite
Brez oznak, prvi označite!
|