Unstable chromosome rearrangements in Staphylococcus aureus cause phenotype switching associated with persistent infections

Staphylococcus aureus small-colony variants (SCVs) are associated with unusually chronic and persistent infections despite active antibiotic treatment. The molecular basis for this clinically important phenomenon is poorly understood, hampered by the instability of the SCV phenotype. Here we investi...

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Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Guérillot, Romain, Kostoulias, Xenia, Donovan, Liam, Li, Lucy, Carter, Glen P., Hachani, Abderrahman, Vandelannoote, Koen, Giulieri, Stefano, Monk, Ian R., Kunimoto, Mayu, Starrs, Lora, Burgio, Gaétan, Seemann, Torsten, Peleg, Anton Y., Stinear, Timothy P., Howden, Benjamin P.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2019
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6778178/
https://ncbi.nlm.nih.gov/pubmed/31527262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1904861116
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