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Prostaglandin E(2) and an EP4 Receptor Agonist Inhibit LPS-Induced Monocyte Chemotactic Protein 5 Production and Secretion in Mouse Cardiac Fibroblasts via Akt and NF-κB Signaling.
BACKGROUND: Prostaglandin E2 (PGE(2)) signals through 4 separate G-protein coupled receptor sub-types to elicit a variety of physiologic and pathophysiological effects. We have previously reported that mice lacking the EP4 receptor in the cardiomyocytes develop heart failure with a phenotype of dila...
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| Udgivet i: | Prostaglandins Other Lipid Mediat |
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| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6778017/ https://ncbi.nlm.nih.gov/pubmed/31229524 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.prostaglandins.2019.106349 |
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