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The TYRP1-mediated protection of human tyrosinase activity does not involve stable interactions of tyrosinase domains.

Tyrosinases are melanocyte-specific enzymes involved in melanin biosynthesis. Mutations in their genes cause oculocutaneous albinism associated with reduced or altered pigmentation of skin, hair, and eyes. Here, the recombinant human intra-melanosomal domains of tyrosinase, TYRtr (19 – 469), and tyr...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Pigment Cell Melanoma Res
Main Authors: Dolinska, Monika B., Wingfield, Paul T., Young, Kenneth L., Sergeev, Yuri V.
Format: Artigo
Jezik:Inglês
Izdano: 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6777992/
https://ncbi.nlm.nih.gov/pubmed/31077632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/pcmr.12791
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