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The TYRP1-mediated protection of human tyrosinase activity does not involve stable interactions of tyrosinase domains.
Tyrosinases are melanocyte-specific enzymes involved in melanin biosynthesis. Mutations in their genes cause oculocutaneous albinism associated with reduced or altered pigmentation of skin, hair, and eyes. Here, the recombinant human intra-melanosomal domains of tyrosinase, TYRtr (19 – 469), and tyr...
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| Publicado no: | Pigment Cell Melanoma Res |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6777992/ https://ncbi.nlm.nih.gov/pubmed/31077632 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/pcmr.12791 |
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