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The consequences of deglycosylation of recombinant intra-melanosomal domain of human tyrosinase
Tyrosinase, a melanosomal glycoenzyme, catalyzes initial steps of the melanin biosynthesis. While glycosylation was previously studied in vivo, we present three recombinant mutant variants of human tyrosinase, which were obtained using multiple site-directed mutagenesis, expressed in insect larvae,...
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| Опубликовано в: : | Biol Chem |
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| Главные авторы: | , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2017
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6108172/ https://ncbi.nlm.nih.gov/pubmed/28858842 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1515/hsz-2017-0178 |
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