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Membrane-associated human tyrosinase is an enzymatically active monomeric glycoprotein

Human tyrosinase (hTyr) is a Type 1 membrane bound glycoenzyme that catalyzes the initial and rate-limiting steps of melanin production in the melanosome. Mutations in the Tyr gene are linked to oculocutaneous albinism type 1 (OCA1), an autosomal recessive disorder. Currently, the application of enz...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Kus, Nicole J., Dolinska, Monika B., Young, Kenneth L., Dimitriadis, Emilios K., Wingfield, Paul T., Sergeev, Yuri V.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5988326/
https://ncbi.nlm.nih.gov/pubmed/29870551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0198247
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