Adipocyte JAK2 mediates spontaneous metabolic liver disease and hepatocellular carcinoma

Nonalcoholic fatty liver disease (NAFLD) and steatohepatitis (NASH) are liver manifestations of the metabolic syndrome and can progress to hepatocellular carcinoma (HCC). Loss of growth hormone (GH) signaling is reported to predispose to NAFLD and NASH through direct actions on the liver. Here, we r...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:JCI Insight
Prif Awduron: Corbit, Kevin C., Wilson, Camella G., Lowe, Dylan, Tran, Jennifer L., Vera, Nicholas B., Clasquin, Michelle, Mattis, Aras N., Weiss, Ethan J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Clinical Investigation 2019
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6777921/
https://ncbi.nlm.nih.gov/pubmed/31393852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.131310
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