Syndecan-1 promotes lung fibrosis by regulating epithelial reprogramming through extracellular vesicles

Idiopathic pulmonary fibrosis (IPF) is a chronic and fatal lung disease. A maladaptive epithelium due to chronic injury is a prominent feature and contributor to pathogenic cellular communication in IPF. Recent data highlight the concept of a “reprogrammed” lung epithelium as critical in the develop...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Parimon, Tanyalak, Yao, Changfu, Habiel, David M., Ge, Lingyin, Bora, Stephanie A., Brauer, Rena, Evans, Christopher M., Xie, Ting, Alonso-Valenteen, Felix, Medina-Kauwe, Lali K., Jiang, Dianhua, Noble, Paul W., Hogaboam, Cory M., Deng, Nan, Burgy, Olivier, Antes, Travis J., Königshoff, Melanie, Stripp, Barry R., Gharib, Sina A., Chen, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6777916/
https://ncbi.nlm.nih.gov/pubmed/31393853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.129359
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