Syndecan-1 Controls Lung Tumorigenesis by Regulating miRNAs Packaged in Exosomes

Syndecan-1 is a transmembrane proteoglycan expressed prominently by lung epithelium and has pleiotropic functions such as regulating cell migration, proliferation, and survival. Loss of syndecan-1 expression by lung cancer cells is associated with higher-grade cancers and worse clinical prognosis. W...

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Detalhes bibliográficos
Publicado no:Am J Pathol
Main Authors: Parimon, Tanyalak, Brauer, Rena, Schlesinger, Saundra Y., Xie, Ting, Jiang, Dianhua, Ge, Lingyin, Huang, Ying, Birkland, Timothy P., Parks, William C., Habiel, David M., Hogaboam, Cory M., Gharib, Sina A., Deng, Nan, Liu, Zhenqui, Chen, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5963476/
https://ncbi.nlm.nih.gov/pubmed/29355516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2017.12.009
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