Syndecan-1 Controls Lung Tumorigenesis by Regulating miRNAs Packaged in Exosomes

Syndecan-1 is a transmembrane proteoglycan expressed prominently by lung epithelium and has pleiotropic functions such as regulating cell migration, proliferation, and survival. Loss of syndecan-1 expression by lung cancer cells is associated with higher-grade cancers and worse clinical prognosis. W...

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Udgivet i:Am J Pathol
Main Authors: Parimon, Tanyalak, Brauer, Rena, Schlesinger, Saundra Y., Xie, Ting, Jiang, Dianhua, Ge, Lingyin, Huang, Ying, Birkland, Timothy P., Parks, William C., Habiel, David M., Hogaboam, Cory M., Gharib, Sina A., Deng, Nan, Liu, Zhenqui, Chen, Peter
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Investigative Pathology 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5963476/
https://ncbi.nlm.nih.gov/pubmed/29355516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2017.12.009
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