miR-323a-3p regulates lung fibrosis by targeting multiple profibrotic pathways

Maladaptive epithelial repair from chronic injury is a common feature in fibrotic diseases, which in turn activates a pathogenic fibroblast response that produces excessive matrix deposition. Dysregulated microRNAs (miRs) can regulate expression of multiple genes and fundamentally alter cellular phe...

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Veröffentlicht in:JCI Insight
Hauptverfasser: Ge, Lingyin, Habiel, David M., Hansbro, Phil M., Kim, Richard Y., Gharib, Sina A., Edelman, Jeffery D., Königshoff, Melanie, Parimon, Tanyalak, Brauer, Rena, Huang, Ying, Allen, Jenieke, Jiang, Dianhua, Kurkciyan, Adrianne A., Mizuno, Takako, Stripp, Barry R., Noble, Paul W., Hogaboam, Cory M., Chen, Peter
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2016
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5135276/
https://ncbi.nlm.nih.gov/pubmed/27942594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.90301
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