Syndecan-1 Attenuates Lung Injury during Influenza Infection by Potentiating c-Met Signaling to Suppress Epithelial Apoptosis

Rationale: Syndecan-1 is a cell surface heparan sulfate proteoglycan primarily expressed in the lung epithelium. Because the influenza virus is tropic to the airway epithelium, we investigated the role of syndecan-1 in influenza infection. Objectives: To determine the mechanism by which syndecan-1 r...

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Detalhes bibliográficos
Publicado no:Am J Respir Crit Care Med
Main Authors: Brauer, Rena, Ge, Lingyin, Schlesinger, Saundra Y., Birkland, Timothy P., Huang, Ying, Parimon, Tanyalak, Lee, Vivian, McKinney, Bonnie L., McGuire, John K., Parks, William C., Chen, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2016
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4970595/
https://ncbi.nlm.nih.gov/pubmed/26959387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201509-1878OC
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