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High-fat diet–induced vagal afferent dysfunction via upregulation of 2-pore domain potassium TRESK channel
Research shows that rats and humans on a high-fat diet (HFD) are less sensitive to satiety signals known to act via vagal afferent pathways. We hypothesize that HFD causes an upregulation of 2-pore domain potassium channels, resulting in hyperpolarization of nodose ganglia (NG) and decreased vagal r...
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| Udgivet i: | JCI Insight |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Clinical Investigation
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6777907/ https://ncbi.nlm.nih.gov/pubmed/31484832 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.130402 |
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