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High-fat diet–induced vagal afferent dysfunction via upregulation of 2-pore domain potassium TRESK channel
Research shows that rats and humans on a high-fat diet (HFD) are less sensitive to satiety signals known to act via vagal afferent pathways. We hypothesize that HFD causes an upregulation of 2-pore domain potassium channels, resulting in hyperpolarization of nodose ganglia (NG) and decreased vagal r...
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| Опубликовано в: : | JCI Insight |
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| Главные авторы: | , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Clinical Investigation
2019
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6777907/ https://ncbi.nlm.nih.gov/pubmed/31484832 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.130402 |
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