Role of prostaglandin D(2) in mast cell activation-induced sensitization of esophageal vagal afferents

Sensitization of esophageal afferents plays an important role in esophageal nociception, but the mechanism is less clear. Our previous studies demonstrated that mast cell (MC) activation releases the preformed mediators histamine and tryptase, which play important roles in sensitization of esophagea...

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Bibliografiske detaljer
Main Authors: Zhang, Shizhong, Grabauskas, Gintautas, Wu, Xiaoyin, Joo, Moon Kyung, Heldsinger, Andrea, Song, Il, Owyang, Chung, Yu, Shaoyong
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2013
Fag:
Neuroregulation and Motility
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3652067/
https://ncbi.nlm.nih.gov/pubmed/23471341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00448.2012
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