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Role of prostaglandin D(2) in mast cell activation-induced sensitization of esophageal vagal afferents

Sensitization of esophageal afferents plays an important role in esophageal nociception, but the mechanism is less clear. Our previous studies demonstrated that mast cell (MC) activation releases the preformed mediators histamine and tryptase, which play important roles in sensitization of esophagea...

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Autors principals: Zhang, Shizhong, Grabauskas, Gintautas, Wu, Xiaoyin, Joo, Moon Kyung, Heldsinger, Andrea, Song, Il, Owyang, Chung, Yu, Shaoyong
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3652067/
https://ncbi.nlm.nih.gov/pubmed/23471341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00448.2012
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