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Computational modeling reveals multiple abnormalities of myocardial noradrenergic function in Lewy body diseases

BACKGROUND: Lewy body diseases, a family of aging-related neurodegenerative disorders, entail loss of the catecholamine dopamine in the nigrostriatal system and equally severe deficiency of the closely related catecholamine norepinephrine in the heart. The myocardial noradrenergic lesion is associat...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Goldstein, David S., Pekker, Mark J., Eisenhofer, Graeme, Sharabi, Yehonatan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6777815/
https://ncbi.nlm.nih.gov/pubmed/31335324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.130441
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