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Intra-neuronal vesicular uptake of catecholamines is decreased in patients with Lewy body diseases

Several neurodegenerative disorders, including Parkinson disease (PD), are characterized by the presence of Lewy bodies — cytoplasmic inclusions containing α-synuclein protein aggregates — in the affected neurons. A poorly understood feature of Lewy body diseases is loss of sympathetic nerves in the...

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Autors principals: Goldstein, David S., Holmes, Courtney, Kopin, Irwin J., Sharabi, Yehonatan
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3148734/
https://ncbi.nlm.nih.gov/pubmed/21785221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI45803
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