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Sympathetic noradrenergic before striatal dopaminergic denervation: relevance to Braak staging of synucleinopathy

Braak's staging concept of Lewy body disease pathogenesis is based on a spatiotemporal sequence of alpha-synuclein deposition, with autonomic nervous system involvement before synucleinopathy in substantia nigra neurons. A patient with primary chronic autonomic failure underwent biennial brain...

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Detalhes bibliográficos
Publicado no:Clin Auton Res
Main Authors: Goldstein, David S., Holmes, Courtney, Sewell, LaToya, Park, Mee Yeong, Sharabi, Yehonatan
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4912215/
https://ncbi.nlm.nih.gov/pubmed/21796351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10286-011-0136-4
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